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Tsuyoshi Hamaguchi Selected Research

Rosmarinic Acid

1/2021Rosmarinic acid suppresses tau phosphorylation and cognitive decline by downregulating the JNK signaling pathway.
10/2020Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer's disease progression.
1/2019Rosmarinic acid suppresses Alzheimer's disease development by reducing amyloid β aggregation by increasing monoamine secretion.
1/2015Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis.

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Tsuyoshi Hamaguchi Research Topics

Disease

14Alzheimer Disease (Alzheimer's Disease)
09/2022 - 06/2006
10Prion Diseases (Transmissible Spongiform Encephalopathies)
01/2022 - 11/2009
8Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
09/2022 - 10/2009
7Amyloidosis
09/2022 - 03/2012
5Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
04/2021 - 11/2008
4Sporadic Creutzfeldt-Jakob Disease
12/2020 - 02/2009
3Myasthenia Gravis
05/2019 - 02/2014
2Acquired CJD
01/2022 - 05/2014
2Inflammation (Inflammations)
04/2021 - 10/2010
2Dementia (Dementias)
10/2020 - 11/2008
2Neurodegenerative Diseases (Neurodegenerative Disease)
03/2018 - 01/2018
2Muscular Diseases (Myopathy)
02/2017 - 09/2009
2Amyloid Plaque
03/2012 - 01/2012
1Transthyretin-Related Hereditary Amyloidosis
08/2022
1Multiple Sclerosis
01/2022
1Anti-N-Methyl-D-Aspartate Receptor Encephalitis
03/2021
1Cognitive Dysfunction
01/2021
1Relapsing-Remitting Multiple Sclerosis
01/2020
1Progressive Multifocal Leukoencephalopathy
01/2020
1Multiple Myeloma
01/2020
1Parkinson Disease (Parkinson's Disease)
01/2020
1Blepharoptosis (Ptosis, Eyelid)
05/2019
1Neuronal intranuclear inclusion disease
05/2019
1Infections
02/2018
1Kuru
01/2018
1Polyneuropathies (Polyneuropathy)
11/2017
1Granuloma
02/2017
1Leukoaraiosis
01/2017
1Atrophy
01/2015
1Myoclonus (Nocturnal Myoclonus)
05/2014
1Thymoma (Thymic Carcinoma)
02/2014
1Trigeminal Neuralgia (Tic Douloureux)
10/2013
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
10/2013
1Hemifacial Spasm
10/2013
1Amyloid angiopathy
01/2012
1Neoplasms (Cancer)
10/2010
1Nonaka type Distal myopathy
09/2009
1Stroke (Strokes)
11/2008
1Cerebral Hemorrhage
11/2008
1Down Syndrome (Down's Syndrome)
11/2008
1Guillain-Barre Syndrome
05/2007
1Orthostatic Hypotension (Postural Hypotension)
01/2007

Drug/Important Bio-Agent (IBA)

13Amyloid (Amyloid Fibrils)IBA
09/2022 - 11/2008
8Proteins (Proteins, Gene)FDA Link
09/2022 - 10/2010
8Prion ProteinsIBA
03/2018 - 10/2010
5Codon (Codons)IBA
01/2022 - 10/2010
4Methionine (L-Methionine)FDA Link
01/2022 - 10/2010
4Rosmarinic AcidIBA
01/2021 - 01/2015
4Biomarkers (Surrogate Marker)IBA
10/2020 - 01/2013
4Peptides (Polypeptides)IBA
11/2015 - 01/2012
3PrionsIBA
09/2022 - 01/2018
3Cholinergic ReceptorsIBA
05/2019 - 02/2014
2Prealbumin (Transthyretin)IBA
08/2022 - 10/2017
2ApolipoproteinsIBA
01/2017 - 11/2008
2CurcuminIBA
01/2015 - 10/2010
2Amyloidogenic ProteinsIBA
04/2014 - 11/2008
2Amyloid beta-PeptidesIBA
12/2009 - 11/2008
1Human Growth Hormone (Saizen)FDA LinkGeneric
09/2022
1tafamidisIBA
08/2022
1Diflunisal (Dolobid)FDA Link
08/2022
1Glial Fibrillary Acidic ProteinIBA
01/2022
1Tissue Inhibitor of Metalloproteinase-1IBA
04/2021
1Tissue Inhibitor of Metalloproteinase-2IBA
04/2021
1Metalloproteases (Metalloproteinases)IBA
04/2021
1CytokinesIBA
04/2021
1PolyphenolsIBA
01/2021
1elotuzumabIBA
01/2020
1Rituximab (Mabthera)FDA Link
01/2020
1Lenalidomide (CC 5013)FDA Link
01/2020
1SaposinsIBA
01/2020
1DNA (Deoxyribonucleic Acid)IBA
01/2019
1Dopamine (Intropin)FDA LinkGeneric
01/2019
1Valine (L-Valine)FDA Link
01/2018
1Isoleucine (L-Isoleucine)FDA Link
01/2018
1Protein AggregatesIBA
01/2018
1Infliximab (Remicade)FDA Link
11/2017
1myricetinIBA
01/2015
1ferulic acid (sodium ferulate)IBA
01/2015
1Masoprocol (Actinex)FDA Link
01/2015
1Glucose (Dextrose)FDA LinkGeneric
01/2015
1CosmeticsIBA
04/2014
1tau Proteins (tau Protein)IBA
08/2011
1AcetylcholinesteraseIBA
10/2010
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
10/2010
1Hormones (Hormone)IBA
10/2009
1Presenilin-1IBA
09/2009
1Flavin-Adenine Dinucleotide (FAD)IBA
11/2008
1PresenilinsIBA
11/2008
1AntibodiesIBA
05/2007
1hydroxide ionIBA
01/2007
1AntioxidantsIBA
06/2006

Therapy/Procedure

3Blood Transfusion (Blood Transfusions)
11/2009 - 02/2009
3Operative Surgical Procedures
11/2009 - 02/2009
2Therapeutics
03/2021 - 06/2006
1Liver Transplantation
08/2022
1Aftercare (After-Treatment)
04/2021
1Artificial Respiration (Mechanical Ventilation)
03/2021
1Thymectomy
02/2014
1Transplantation
10/2013
1Electrodes (Electrode)
10/2009